Viewing or changing internal standard exceptions

Requirement: Ensure that the internal standard data is within the acceptable limits defined for the laboratory.
Note: The QUAN Review application does not display samples assigned as Solvent (sample type) or raise exceptions against them for the IS Response, IS rt, and IS Absolute Response rules.

To view or change internal standard exceptions:

  1. On the OVERVIEW tab, in the sidebar, click Internal Standards.
  2. To edit internal standard information, in the upper-right corner, click .
  3. To apply or remove the exception filters IS Response, IS rt, and IS Absolute Response, use the filter at the top of the page.
    Note: The exceptions appear as red markers on the graphs. The key adjacent to each graph describes the shape and color of different sample types. Samples that are exceptions maintain their shape but are filled with red.
    Tip: If the filter is active, a check mark appears on the filter. The filter also displays the number of exceptions on it.
  4. To view or change information for an individual IS point, click the individual point in Response deviation, Retention time deviation, or Absolute response deviation IS graphs.
  5. To stack graphs, click .
  6. To overlay graphs, click .
  7. To change the lift off or touch down % for the integration parameters, expand Integration settings, specify a value in the Lift Off or Touch Down box or both, and then click Apply.
  8. To apply the integration changes to all injections, select Update method to apply to all injections.
    Note: After you apply changes to all injections, review integration results across the complete data set to assess any changes made.
  9. To go back to the overall IS graphs, click Back.
  10. To save your changes, in the upper-right corner, click .
  11. To discard the changes, click .