Creating internal standard details

Requirement: Use internal standards (IS) in data reviewed using the QUAN Review application. Ensure that you use the IS Expected Absolute Response rule to raise exceptions where an IS peak is not detected by enabling the rule in the rule set and defining both an Expected IS Absolute Response and an Expected IS Absolute Response tolerance (%) for each internal standard in the method. If a method does not have an Expected IS Absolute Response tolerance (%) characterized, you may use a value of 100% to raise exceptions where internal standards have not been detected.
To create internal standards for a new method, use the Internal Standards page to add each type of internal standard detail:
  • Internal Standards
  • Processing
  • Integration
  • Ion Ratios
  • System Suitability
  • Flagging