Using the default rule set
In the QUAN Review application, you have the option to use a default rule set. To see it, click View default rule set.
The default rule set includes the following rules:
- The R-squared value rules:
Recommendation: Use only one of the following R-squared value rules.
- With the R Squared Value rule, the R-squared value cannot be less than 0.9700 for fitting a valid linear regression line.
- With the R Squared Value (Method) rule, the R-squared value cannot be less than the value defined for the analyte in the flagging parameters of the processing method for fitting a valid linear regression line.
- The deviation of standard and QC injections must be ±20% or the injection will be an exception.
- The calculated signal-to-noise value for the injection cannot be less than 3.
- The response in a blank injection cannot be greater than 20% of the area of the LLOQ injection for that analyte.
- The response of the internal standard must be within ±20% of the median response of that internal standard in the batch.
- The detected retention time of the internal standard must be within ±1.5 sec of the expected retention time.
- The response of the internal standard for every Standard, QC, Unknown, or Blank injection must be within the range defined by the flagging parameters of the method.
- The retention time must be ±1% from the mean detected retention time of the quan reference peaks.
- The Ion Ratio must be ±30% from the mean ion ratio of the quan reference peaks.
- The Quan Ion must be detected for every Standard or QC injection that has a non-zero concentration level set for the analyte.
- The detected retention time of the analyte must be within ±3.0 sec of the expected retention time.