The ACQUITY Premier System with Multi-Dimensional Technology offers the lowest dispersion system for maximum peak capacity with the most reliable, highest performing solvent managers and valve compartments on the market to ensure accuracy and precision of the entire assay. In addition, the system extends the performance of MaxPeak High Performance Surfaces (HPS) Technology beyond the column and have been built to overcome interactions of analytes with metals and metal surfaces by providing the robustness capabilities necessary to support the benefits of sub-2-μm particles, with a surface that mimics the desirable properties of PEEK.