Robust and Reproducible

Rigorous validation of the complete solution has been implemented during the development and manufacture of the system with extended testing across multiple systems. The tests comprise complete biopharmaceutical methods, from sample to reported result, with application-relevant acceptance criteria that meet biopharmaceutical industry standards.

The BioAccord LC-MS System is operating in academic, biopharmaceutical and contract laboratories worldwide, generating consistent and reproducible results every day.

Data Quality

Customer feedback highlighted the need for a small, simple LC-MS system that generates the highest possible data quality.

The BioAccord was developed to meet these requirements, while also delivering the chromatographic resolution, mass resolution, sensitivity, mass accuracy and linearity to meet the needs for a wide range of routine biopharmaceutical analyses.

Chromatogram shows total ion chromatograms (TICs) overlay from 18 injections of the Waters mAb Tryptic Digest Standard (NISTmAb tryptic digest) offers reproducible chromatographic separation for peptides using shallow gradient method.

Addressing Your Applications

Whether your work involves analyzing biomolecules at the intact, subunit, peptide, or released glycan level, the BioAccord System comes with optimized compliance-ready workflows so you can get up and running right away. These include:

• Intact mass analysis of proteins and oligonucleotides
• Subunit analysis of monoclonal antibodies (mAbs)
• Peptide mapping/MAM (multi-attribute method)
• Released N-glycan analysis

Optimized workflows for released glycan analysis include our RapiFluor-MS label, which offers unparalleled fluorescense and MS sensitivity for accurate glycan profiling.

Compliance

Although the system can be used easily in research and early development environments, it has all the tools for adoption by the demanding regulatory environments of late development and QC.

Waters has provided LC and MS solutions for regulated laboratories for many years. Building on this expertise, the BioAccord is the first truly compliance-ready LC-MS system.

With a complete audit trail, configurable access controls and the protection of an Oracle database this system has everything you need to ensure data integrity and meet 21 CFR part 11 and Annex 11 requirements.

The waters_connect informatics platform that automates data acquisition, processing and reporting benefits from decades of industry leadership in developing compliance-ready informatics with Empower and UNIFI.

Productivity

The BioAccord System is designed to give you maximum productivity from your investment. With its SmartMS features, optimized workflows, and application specific release testing, the BioAccord System empowers users of all abilities to run routine biopharmaceutical analyses so your ms experts can focus on the research and discovery work they do best.

Our outcome-based services, which include application specific installation and training from our professional services team, are designed to get you quickly up and running so you can start generating results sooner.

Support

Our service and professional services teams are here to support you from the moment you place your order. An implementation manager is assigned to work through any pre-installation requirements and to schedule the engineer to install and qualify your system.

As part of the BioAccord System experience, one of the applications specialists from our professional services team will work with you and ensure you are getting everything you need from your system – their goal is your success.

Once you are up-and-running we have a flexible range of support plans to ensure you get the most out of your system.

Learn more about our customer support.