Symmetry HPLC Columns for Reproducibility

You can rely on a Symmetry HPLC column for rugged and reproducible performance. Narrow column specification ranges minimize variation giving you the confidence that the methods you use today will continue to be used in the future.

Symmetry Shield Columns for Superior Peak Shape

SymmetryShield™ Columns feature Waters' patented embedded polar group technology that shields the silica's residual silanols from highly basic analytes at improves overall peak shape. Additionally, by placing the embedded polar group close to the silica surface, the activity of the surface silanols is further reduced.  This imparts selectivity and retention that is different compared to the Symmetry C₁₈ ligand.

Embedded polar group technology improves chromatographic peak shape and selectivity.

Symmetry300 Columns Deliver High Peptide Recovery

All Symmetry300™ columns are QC tested with peptide samples to ensure exceptional batch-to-batch reproducibility.  These wide-pore (300Å), reversed-phase chromatography columns deliver superior performance when simultaneously separating hydrophilic and hydrophobic peptides, as well as neutral and highly basic peptides. Expect better performance using either high or low mass loads with a Symmetry300 column.

Symmetry300 C₄ Columns provide superior peptide separation.

VanGuard Column Protection

The often complex sample matrices encountered in pharmaceutical, natural product, environmental, and industrial chemical analysis prematurely shorten analytical column lifetime and degrade chromatographic performance. Waters VanGuard Cartridge Columns help improve analytical column performance by removing particulate and chemical contamination that may be present in the mobile-phase stream—without compromising chromatographic performance.