Mass Spectrometry Ion Sources

When you need to extract the maximum amount of information from a diverse range of compounds, you require the ultimate in ionization flexibility and performance.

Providing the highest performance, without compromise, the ionization source options are quick and easy to interchange enabling the widest range of ionization techniques to be utilized universally across a single analytical platform.


UniSpray Ion Source Generate more free ions when compared to electrospray ionization and other traditional modes with the Waters UniSpray Ion Source.
ionKey/MS Integrate microflow UPLC separation power directly into the mass spectrometer’s ion source with the iKey and ionKey/MS System for LC-MS system performance and sensitivity.
Waters Atmospheric Pressure Gas Chromatography (APGC) Source Achieve ultra-trace levels in complex samples and confident compound identification without analytical compromise with Waters Atmospheric Pressure Gas Chromatography (APGC), a GC-MS source.
LockSpray Exact Mass Ionization Source The LockSpray™ dual electrospray ion source optimizes the co-introduction of analyte and lock mass compound directly into the ion source, providing authenticated exact mass measurement in MS and MS/MS modes.
NanoLockSpray Exact Mass Ionization Source The NanoLockSpray™ dual electrospray ion source accessory with optimized co-introduction of analyte and lock mass compounds provides authenticated exact mass measurement in NanoFlow™ LC/MS and LC/MS/MS modes of operation.
IonSABRE APCI Probe Accessory APCI is an effective method for analyzing lower-polarity compounds. The high-efficiency IonSABRE™ APCI probe offers significant improvements in sensitivity compared with earlier versions of probe, particularly at higher liquid flow rates.
Atmospheric Solids Analysis Probe The Atmospheric Solids Analysis Probe is a useful tool for the rapid direct analysis of volatile and semi-volatile solid and liquid samples using atmospheric pressure ionisation.
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Fundamentals of MS Videos What is Mass Spec?

Learn the principles of MS through these quick videos
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View recorded webinar: Quantitative Analysis at Microfluidics Flowrates - Sensitivity and Robustness

Discover the technology behind ionKey/MS and the benefits in sensitivity gain and reduction of matrix influence on sample analysis.
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