Streamlined, Compliance-Ready Biopharmaceutical Workflows

The BioAccord LC-MS System comes installed with pre-optimized biopharmaceutical workflows for:

• Intact Mass Analysis of Proteins & Oligonucleotides
• Monoclonal Antibody (mAb) Subunit Analysis
• Released N-Glycan Analysis
• Peptide Mapping/MAM Analysis

Each workflow provides for compliance-ready data acquisition, processing and reporting with optimized default settings, automated data processing and reporting capabilities, and full audit trail capabilities.

Intact Analysis

• Proteins/monoclonal antibodies (mAbs)

• Antibody Drug Conjugates (ADCs)

• Oligonucleotides

Intact Analysis Application notes:

A Platform Method for the Molecular Mass Analysis of the Light Chains and Heavy Chains of Monoclonal Antibodies using the BioAccord System

Analysis of Antibody Drug Conjugates (ADCs) by Native Mass Spectrometry on the BioAccord System

Enabling Routine and Reproducible Intact Mass Analysis When Data Integrity Matters

mAb Subunit Analysis

mAb Subunit Analysis Application Notes:

Online IEX-MS of mAb Charge Variants Using a BioResolve SCX mAb Column, IonHance CX-MS pH Concentrates, and BioAccord System

Released N-Glycan Analysis

Released N-Glycan Analysis Application Notes:

Released N-linked Glycan Analysis Using the BioAccord System

Increasing Productivity and Confidence for N-linked Glycan Analysis of Biosimilars Using the BioAccord System

Peptide Mapping/MAM

Peptide Mapping/MAM Application Notes:

Routine Peptide Mapping Analysis using the BioAccord System

Establishing an Integrated Peptide Attribute Profiling and Monitoring Workflow for Improved Productivity and Confidence