上游生物工艺开发

尽在掌控:自主获取优质数据,加快决策速度

为尽可能提高药品质量和产量,上游生物工艺开发工程师需要对细胞系和制造工艺进行更有效且数据驱动的优化。获取产品质量属性(PQA)或培养基信息通常需要等上长达6周的时间,这极大地阻碍了制定明智决策的效率,可分析的样品数量也因此受限。

我们相信工艺工程师能够轻松地给出这些结果。沃特世与赛多利斯合力开发出一套特有的方法,能够在克隆选择和生物工艺开发过程中直接测定PQA和细胞培养基特性。

Sartorius Ambr® 15多并行生物反应器系统现在具有专用工作流程以及与Waters BioAccord LC-MS系统相连接的优势,可大幅提高药品原液质量和产量,大幅减少下游杂质并加快开发工作 — 节省时间和多个优化周期的成本(高达50,000美元/周期)。
   • 关联工艺输入和产品质量输出:在同一平台上监控细胞培养基特性和产品属性
   • 持续的产品质量反馈:尽早掌握指标结果,以近乎实时的速度制定决策
   • 搭配BioAccord LC-MS系统使用:这是一款面向非专家用户推出的的平台,拥有高通量并且易于部署和操作,能够无缝运行生物工艺分析工作流程

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Bioprocess Walk-Up Solutions Perform routine LC-MS analysis on upstream bioprocess bioreactor samples with easy-to-use walk-up solutions from Waters, designed for bioprocess engineers.
Upstream Bioprocess Development Accelerate upstream bioprocessing development, including cell culture media analysis and product quality attribute analysis, with Waters BioAccord LC-MS System and Sartorius Ambr 250 HT Multi-parallel Bioreactors.
Cell Line and Clone Selection Enhance your cell line development workflow with the LC-MS systems built for Upstream Bioprocessing Development from Waters Corporation.
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Accelerating upstream process development with direct CQA
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Take Control of Your Bioprocess Development
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Waters and Sartorius Collaborate to Accelerate Bioprocess Development
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Evolving Analytics in the Upstream Lab by Using the Power of LC-MS
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