Dioxins and Furans

Dioxin analysis is complex, with low level regulatory limits and complex sample matrices. With cutting-edge instrumentation and solutions from Waters, laboratories in food, feed and environmental industries can make increasingly sensitive dioxin and furan measurements.

Dioxin analysis is complex, with low level regulatory limits and complex sample matrices. With cutting-edge instrumentation and solutions from Waters, laboratories in food, feed and environmental industries can make increasingly sensitive dioxin and furan measurements.

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Overview

Dioxins are bio-accumulative persistent organic pollutants (POPs) largely formed during combustion processes and are found throughout the environment. Dioxin analysis is particularly demanding due to low level regulatory exposure limits and complex sample matrices.

Cutting-edge instrumentation, such as Waters Xevo TQ-XS with APGC, enables laboratories in food, feed, and environmental industries to make increasingly sensitive measurements from complex samples and allows updated recommendations to be made on regulatory limits. With Waters solutions, you can:

Confidently adopt APGC-MS/MS as an alternative to traditional HRMS analysis for best-in-class sensitivity
Exceed analytical performance of legacy magnetic sector instruments and electron ionization MS/MS systems offered by other manufacturers
Improve robustness for increased productivity
Support success with commercial laboratory validation and regulatory acceptance

Applications

Dioxins and Furans Analysis

Polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), and polychlorinated biphenyls (PCBs) are toxic compounds categorized as persistent organic pollutants (POPs), commonly known as dioxins and furans, bringing considerable health risks. Approval of a new method that uses GC-MS/MS to determine these compounds takes advantage of the advances made in tandem quadrupole MS over the decades, offering the potential to lower laboratory costs.

Polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), and polychlorinated biphenyls (PCBs) are toxic compounds categorized as persistent organic pollutants (POPs), commonly known as dioxins and furans, bringing considerable health risks. Approval of a new method that uses GC-MS/MS to determine these compounds takes advantage of the advances made in tandem quadrupole MS over the decades, offering the potential to lower laboratory costs.

Application Notes

Case Study: SGS AXYS and Waters Validate APGC as New Methodology for Dioxin and Environmental Contaminants Analysis

Using Waters APGC coupled with the Xevo TQ-XS Triple Quadrupole Mass Spectrometer, scientists at SGS AXYS worked closely with Waters to develop and validate an alternative procedure for polychlorinated dibenzo dioxins and furans by EPA method 1613B using GC-MS/MS, at the request of US EPA. This case study highlights the numerous benefits this method offers for dioxin and environmental contaminant analysis.

Using Waters APGC coupled with the Xevo TQ-XS Triple Quadrupole Mass Spectrometer, scientists at SGS AXYS worked closely with Waters to develop and validate an alternative procedure for polychlorinated dibenzo dioxins and furans by EPA method 1613B using GC-MS/MS, at the request of US EPA. This case study highlights the numerous benefits this method offers for dioxin and environmental contaminant analysis.

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Solutions

Waters LC-MS and GC-MS systems offer absolute performance in separation and sensitivity for dioxins and furans analysis.

Absolute power to easily quantitate your most challenging compounds

Absolute power to easily quantitate your most challenging compounds

Xevo TQ Absolute Triple Quadrupole Mass Spectrometry

Achieve and maintain high performance and productivity with significantly increased sensitivity for negative ionizing compounds with the Xevo TQ Absolute, Waters compact, sustainable tandem quadrupole mass spectrometer.

Superior performance in your routine quantitative analyses

Superior performance in your routine quantitative analyses

Xevo TQ-XS Triple Quadrupole Mass Spectrometer

Improve your laboratory productivity and capabilities with Waters Xevo TQ-XS Triple Quadrupole Mass Spectrometer that adds adaptability and flexibility to your analytical capabilities for easy detection.

Complete coverage for confident characterization

Complete coverage for confident characterization

Xevo G3 QTof

Maximize sample information for your analytes from detailed characterization to accurate quantitation with the Xevo G3 QTof and ensure you can keep pace with the changing demands on your laboratory.

No compromise atmospheric pressure ionization GC-MS

No compromise atmospheric pressure ionization GC-MS

Waters Atmospheric Pressure Gas Chromatography (APGC) Source

Discover the benefits that Waters APGC Source offers to your laboratory in terms of operational efficiency, analytical quality, and cost savings to overcome the typical limitations of vacuum-based systems and improve confidence in analyte identification.

Performance that advances your lab

Performance that advances your lab

ACQUITY UPLC H-Class PLUS System

Improve laboratory productivity by enhancing the characterization of your complex samples using Waters ACQUITY UPLC H-Class PLUS System that offers improved resolution and advanced tools to simplify and streamline your method development workflow.

Waters software streamlines data acquisition, processing, and reporting of consistent results.

Lab informatics designed to advance your scientific and business outcomes

Lab informatics designed to advance your scientific and business outcomes

waters_connect Informatics Platform

Facilitate faster and more robust analyses with waters_connect Informatics Platform that has a suite of scientific analysis products such as system and data management, analytics, and concurrent collaboration to improve efficiency, ensure reproducibility, and reduce errors.

The reproducibility and flexibility you need for all your separations

The reproducibility and flexibility you need for all your separations

Column Particle Technologies

Simplify the process of maximizing column performance and column lifetimes for better peak shape, efficiency, and reproducibility with Waters Column Particle Technologies that help you achieve your separation goals.

Achieve high analytical performance and accurate results using streamlined Waters services and support.

Your success is just a click away

Your success is just a click away

Waters Global Services

Optimize your laboratory's productivity and success with Waters Global Services to maintain peak system performance, minimize downtime, address application challenges, and support stringent compliance requirements.

Make science more accessible with Waters Capital

Make science more accessible with Waters Capital

Payment Solutions

Maximize resources and minimize risk with payment options from Waters Capital, including upgrading aging equipment, getting customized support, and bundling services into one monthly payment.

The data speaks for itself

Evaluation of robustness of electrospray (blue) and UniSpray (orange) over 30 injections of a surface water sample.

Results from fly ash QC sample.

Residuals plot and linear regression of a five point calibration of 2378-TCDD ranging from 0.5 pg to 200 pg run on APGC-QTof. 5b. Standard reference sediment NIST1944 (ng/kg dry-mass) extracted by the modified QuEChERS method and analyzed by GC-HRMS and with APGC-QTof. Comparison run on a 40 m Rtx-Dioxin2 column with a flow rate of 1 mL/min.

Comparison of the unknown compound spectra from Population 1 to a standard of BTH at 1 ppm.

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